Vitamin K includes a group of compounds that contain a central ring structure with varying side chains. These differing side chains account for differences in absorption, bioavailability, transport and tissue distribution. Vitamin K1, phylloquinone, is the most common form and is found in plants and green vegetables. The vitamin K2 family, menaquinones, are less common and are found in meats, eggs, some cheeses, and fermented food, such as Japanese natto. The most common menaquinones are menaquinone-4 and menaquinone-7 (MK-7). Studies indicate that vitamin K1 and vitamin K2 (menaquinone-4) are primarily concentrated in the liver, while MK–7 is concentrated in extra–hepatic tissues, including vascular tissues. MK-7 also has a longer half–life. This unique formula contains a broad-spectrum blend of vitamins K1, K2 and D for healthy calcium utilization to maintain healthy bones and blood vessels.
- Supplement Facts
- 1–2 capsules per day, in divided doses, with meals.
- each vegetable capsule contains
- vitamin D3....................................................................................... 200 i.u.
- vitamin K1 ................................................................................... 500 mcg.
- vitamin K2 (menaquinone-4)............................................................... 1 mg.
- vitamin K2 (MK-7) (derived naturally from natto)†........................... 45 mcg.
- (hypo-allergenic plant fiber added to complete capsule volume requirement)
- Contains milk, soy
- Not to be taken by pregnant or lactating women. Not for individuals
- taking blood thinning medications.
Uses:
Bone Health: Vitamin K enhances bone formation by carboxylating osteocalcin. This enables osteocalcin to bind to calcium and promote healthy bone mineralization. Vitamin D synergistically regulates the synthesis of osteocalcin by osteoblasts in bone. Adequate intake of vitamin K1 and K2 may be especially important for optimal carboxylation in aging individuals, as indicated by a recent study involving Japanese women. Vascular Health: Vitamin K dependent proteins in the liver are responsible for maintaining healthy blood coagulation and platelet function. Additionally, by activating matrix Gla-protein (MGP), vitamin K also helps maintain healthy calcium metabolism in vascular tissues, supporting healthy vascular elasticity. Recent studies indicate that vitamin D potentiates the activity of MGP and that the combination of vitamin K and D provides synergistic support for blood vessel function.
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