Butterbur is a perennial shrub with a 2,000-year history of traditional use. In the last twenty-five years, it has been trusted extensively throughout Europe by neurologists and other health professionals. It has been studied for healthy cranial vessel support.

• Supplement Facts
• 2–3 capsules per day, in divided doses, with meals.
• each softgel capsule contains
• butterbur (Petasites hybridus) extract (28-44:1) (root) .............. 48-52 mg
• (standardized to contain 7.5 mg of petasin and isopetasin)
• other ingredients: riboflavin, glycerol, gelatin capsule, sorbitol

Uses:

Cranial Vessel Support: In one clinical trial with 60 participants, Petadolex showed the potential to support cranial vessel comfort and was well tolerated. After a twelve-week period, almost eighty percent of participants supplementing with Petadolex indicated a supportive effect. In part, the mechanism for this action may involve a supportive spasmolytic effect on smooth muscle in cranial blood vessels. A second study with 229 individuals indicated similar positive results. In this trial, optimal dosing of Petadolex provided significant support compared to placebo within one month. After three months, over seventy percent of individuals experienced a positive outcome.
Maintain Healthy Histamine Release: A petasin-containing butterbur extract has been shown to maintain healthy histamine and cytokine release. In two clinical trials, butterbur maintained healthy nasal histamine release and leukotriene activity, supporting both subjective and objective parameters.